I've been posting about my sick fish, Tuna Bob, in this thread -
http://www.bettafish.com/showthread.php?t=113393 - because he had some of the same symptoms and Sakura and BritishBetta where both very helpful. However, he's just not getting any better so I thought I'd stop hijacking BB's thread and start my own in case I'm dealing with something entirely different.
Housing - NOTE: This pertains to his current hospital setup - normally he is in a 5 gallon filtered, cycled, heated tank with 50% water changes weekly.
What size is your tank? 1 gal
What temperature is your tank? +/- 84
Does your tank have a filter? no
Does your tank have an air stone or other type of aeration? no
Is your tank heated? Yes
What tank mates does your betta fish live with? None
Food
What type of food do you feed your betta fish? NLS and Betta Buffet, occasional bloodworm
How often do you feed your betta fish? 2x day, 2-3 pellets each time
Maintenance
How often do you perform a water change? daily (weekly when in 5 gal)
What percentage of the water do you change when you perform a water change? 100% (50% in 5 gal)
What type of additives do you add to the water when you perform a water change? StressCoat
Water Parameters:
Have you tested your water? If so, what are the following parameters?
Ammonia: 0-.25
Nitrite: 0
Nitrate: 5-10 (I have well water and it's always at this level or higher. I control it with Purigen in his filter in his 5 gallon tank)
pH: 7.8
Hardness:
Alkalinity:
Symptoms and Treatment
How has your betta fish's appearance changed? Eyes became "bulgy"

2 weeks ago. I watched him for about a week to see if I was imagining it since he had no other symptoms and 1 week ago decided they were indeed bulging and began treatment for popeye with Epsom salt only.
How has your betta fish's behavior changed? In the last week, became more lethargic. Belly has turned grey. He was slightly pineconed for a day or so but Epsom seems to have helped that. Last 2-3 days, barely moves except to get air. However, he is still eating, pooping, not bloated, and usually comes to greet me when I look at him.
When did you start noticing the symptoms? 2 weeks ago
Have you started treating your fish? If so, how? Yes - Epsom Salt 2 tsp/gallon and Maracyn 2 started Sunday thru yesterday. API General Cure Wednesday and Today.
Does your fish have any history of being ill? Has lymphocystis, but doesn't seem to bother him. Other than that, very healthy and active.
How old is your fish (approximately)? I've had him 5 months, got him from Petco. Less than a year old?
So, I've finished the 5 days of Maracyn 2. I didn't combine it with Maracyn 1 because I initially thought I was just dealing with popeye. And maybe I am.....I just don't know. Also, I didn't realize the Maracyn may not work in high PH, so maybe it didn't do a thing for him anyway. He doesn't seem to be any better and I'm wondering what, if anything, I should try next. Should I just give the Epsom salt a little more time or attack whatever this is with a different antibiotic, with the caveat I'm limited to whatever I can find at Petsmart (Petco has zilch - apparently it's more profitable to just sell you new fish)? I definitely understand the hesitancy to overuse antibiotics and don't for myself or my other animals, but I know how to take care of a dog or a cat or a horse....I'm still pretty clueless with fish and I panicked.
On the other hand, he hasn't gotten any worse in the last 2 days and is still eating and pooping - always a good thing.
I REALLY REALLY like this little fish

.....he's normally such a character. I REALLY want to save him.
Any thoughts or advice is appreciated.