Jada, I'm so sorry about your cat. :( Big HUGS for you.
Now, about Nano. Hmm.
Here's the thing. If he has flukes, then A) you won't be able to see them so you won't be able to tell if they're gone, so no worries about that part and B) the temp should go UP for flukes because higher temps shortens the life spans of most external parasites.
In the case of General Cure. It's confusing and I actually found the same confusing info for praziquantel when I needed to deworm a cat. Must be a prazi thing.
Anyway, I would go ahead and do at least 4 doses, probably 6.
You can combine General Cure with Kanaplex and Furan-2 to make an extremely powerful drug combination but in this case, you probably only need the Kanaplex.