Kind of confused about maracyn plus dosing

[aemaki09]

The directions on the maracyn plus bottle say "treat on day 1, 3, and 5."

I know there is probably nothing to be confused about, but I feel like I should be doing water changes between those days for some reason. Maybe because with every other medication I've used I have had to do them?

Anyways, are these directions as straight foreward as they sound, or do I really need to do changes?

[LittleBlueFishlets]

I wasn't able to find Mardel's website. But I found a similar product:
Fish Sulfa Forte (Sulfamethoxazole 800mg, Trimethoprim 160mg)

[Maracyn Plus contains Sulfadimidine/Trimethoprim. Sulfamethoxazole (in Forte) and Sulfadimidine (in Maracyn+) are both"Sulfa" drugs.]

The Fish Sulfa Forte directions state:
"Add one tablet (960 mg) into aquarium for each 40 gallons of water to be treated. Repeat in 24 hours. It is suggested that a partial water change be made between treatments. While duration of treatment depends on type and severity of infection, it is recommended that extended baths in the medication continue for a minimum of 5 days & for not more than 10 days. Discontinue treatment with this medication if no improvement is noted within 5 days. To remove harmless yellow color, change 20% of water and use charcoal filter until clear."
http://www.fishmoxfishflex.com/index...lfa-forte.html

I'm going to continue looking for Mardel's website. I'm also going to try to find out about the half-lives of the meds in water, and whether they'd persist for a long time before breaking down, or if they break down quickly....

[Jeneddi]

I've always dosed the 3 times and then changed the water after the course was finished. Hopefully they would tell us if we needed to be changing the water every other day

[LittleBlueFishlets]

Found the Mardel website: www.sentrypetcare.com

You can ask questions via their site. Go here to submit it:
http://www.sentrypetcare.com/Contact...ct.asp?faq=faq

[LittleBlueFishlets]

Originally Posted by Jeneddi

I've always dosed the 3 times and then changed the water after the course was finished. Hopefully they would tell us if we needed to be changing the water every other day

I agree.... I think you should do the entire "treatment" and then change the water.

I think this is what the Forte instructions may be saying. That you complete the entire 5-10 day treatment "cycle," then do a partial WC. (See post below....)

[LittleBlueFishlets]

Originally Posted by LittleBlueFishlets

The Fish Sulfa Forte directions state:
"...It is suggested that a partial water change be made between treatments. While duration of treatment depends on type and severity of infection, it is recommended that extended baths in the medication continue for a minimum of 5 days & for not more than 10 days.... "
http://www.fishmoxfishflex.com/index...lfa-forte.html

When I read the bolded/underlined sections, it sounds to me like they're defining a "treatment" as a 5-10 day period.... And they recommend a water change after the "treatment cycle" is complete.....

[LittleBlueFishlets]

*Grumble* I found the answer on page 384 --- in a book that costs $109.... *Grumble*

I think going to the Mardel website that I posted above and asking them is probably the best way to do it.

[aemaki09]

Thanks! Lol I'll ask them. I'm going to assume that I dot need the water changes until the 6th day unless they tell me itherwise