Originally Posted by kyle89
Large water changes is the only way to get the nitrite down and wouldn't it be pointless to add safestart if you are doing water changes. Your just removing the safe start?
The bottle says to wait about a week after adding, in order to allow the bacteria time to adhere to the substrate, decor, and filter media.
However, you'll want to keep an eye on ammonia levels during that time. If they get out of hand, you'll want to do a small water change to keep the fish safe, regardless of what the directions say (I suppose you could remove the fish too, and avoid changing the water). I didn't have problems with nitrites though when I used safestart, but ammonia was persistent at around 0.25-0.5 ppm.