^ Everyone except me that is!
If water changes required me to swallow water containing fish waste, I would drop this hobby like a hot potato.
So if you're pathetically squeamish like me, this is a suck-free way to start suction on a siphon:
1.) Tightly cover the hole on the small tube with your thumb, making sure no air can escape. Hold the large tube vertically in your other hand.
2.) Then fill the large tube to the rim with water. (It can be aquarium water or tap water...I prefer water from the tap just because it's less messy.)
3.) Still keeping the small end covered with your thumb and holding the larger tube vertically, raise the larger tube to a level above the smaller end. Gently swirl the larger tube to allow any air to bubble up. It helps a lot if you let the middle of the hose gently tap against a counter as you swirl the larger end. The larger tube should now only be partially filled with water.
4.) Still holding the larger tube vertically and keeping the smaller tube covered, immerse the larger tube into the aquarium, open end facing up. Allow air to bubble out, then invert. Now you place the smaller tube in a bucket (try not to let it fall out of the bucket, otherwise you'll have a wet floor) and remove your thumb from the end. The water should start siphoning into the bucket.
^ If you find it hard to visualize the above directions, here's a nice video demonstration:
Note: Be sure to not let the bucket overflow. ;)