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Oh dear poor thing. That looks like severe tail rot turning into body rot. Likely caused by poor water conditions (not changing the water enough and keeping in too small a tank).

Do a 100% water change daily, and you will likely need a very strong antibiotic if you want to try to save him. It looks like he could certainly die from his condition.

I am not an expert on which antibiotic to choose, but my best guess would be using both Kanaplex plus Nitrofurazone. Or perhaps Tetracycline?
 
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